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MRT68921 HCl
CAS No. 2070014-87-6
MRT68921 HCl ( —— )
产品货号. M20090 CAS No. 2070014-87-6
MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM respectively).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥486 | 有现货 |
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| 10MG | ￥770 | 有现货 |
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| 25MG | ￥1604 | 有现货 |
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| 50MG | ￥2900 | 有现货 |
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| 100MG | ￥3613 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称MRT68921 HCl
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM respectively).
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产品描述MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM respectively).
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同义词——
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通路Autophagy
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靶点Autophagy
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受体ULK1; ULK2
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研究领域——
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适应症——
化学信息
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CAS Number2070014-87-6
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分子量471.04
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分子式C25H34N6O·HCl
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纯度>98% (HPLC)
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溶解度DMSO: 10 mg/mL;Water: 10 mg/mL
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SMILESCl.CN1CCc2cc(Nc3ncc(C4CC4)c(NCCCNC(=O)C4CCC4)n3)ccc2C1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Lys05
Lys05 (Lys01 trihydrochloride, PS-1001)is the water-soluble salt of Lys01, is a 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ); shows IC50 values of 3.6, 3.8, 6 and 7.9 uM for 1205Lu, c8161, LN229 and HT-29 cell line in the MTT assay.
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Sulfamethizole
Sulfamethizole is a sulfathiazole antibacterial agent.
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LYN-1604 2HCl 221675...
LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.LYN-1604, to be the best candidate for a ULK1 agonist.LYN-1604 induced cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.LYN-1604 has potential for good therapeutic effects on TNBC by targeting ULK1-modulated cell death in vivo.
